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E. coli nitroreductase : ウィキペディア英語版 | E. coli nitroreductase ''E. coli'' nitroreductase is a flavoprotein found in the bacteria ''Escherichia coli''. It catalyses the reduction of nitro groups in a wide range of substrates to produce the corresponding hydroxylamine. Although its role ''in vivo'' is unclear, it has been identified as useful in the metabolism of a number of prodrugs in anti-cancer gene therapy.〔Denny, W.A. "Nitroreductase-based GDEPT" ''Current Pharmaceutical Design'', 2002, 8(15), 1349-1361.〕 ==See also==
* Reduction of nitro compounds
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